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Infekční peritonitida koček (FIP)

Infekční peritonitida koček je smrtelná virová infekce domácích a divokých koček způsobená specifickým kmenem viru zvaným kočičí koronavirus. Vzhledem k tomu, že u koček produkuje alfa koronaviry, liší se od koronaviru SARS-Cov-2, který u lidí produkuje COVID-19, beta alfavirus. FCoV se vyskytuje u koček chovaných v domácím i venkovním chovu. Míra infekce dramaticky stoupá v domácnostech s více vrhy ve srovnání s domácnostmi s jednou kočkou.

Přestože kočičí koronavirus (FCoV) způsobuje u koček pouze mírný průjem, jeho mutovaný kmen může vést k vážnému onemocnění, které může u koček vést k úmrtí. Asi u 10 % nakažených koček se rozvine infekce známá jako virus infekční peritonitidy koček (FIPV), která se může šířit po celém těle. Když se onemocnění zhorší, začne postihovat ledviny, břicho a mozek.

What Is Feline Calicivirus (FCV)?

Feline calicivirus is a highly contagious RNA virus belonging to the Caliciviridae family. It is a core component of the feline upper respiratory disease complex and is endemic in cat populations globally.

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Search terms such as feline calicivirus, calicivirus cats, FCV in cats, and cat FCV all refer to the same viral infection.

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Infekční peritonitida koček je smrtelná virová infekce domácích a divokých koček způsobená specifickým kmenem viru zvaným kočičí koronavirus. Vzhledem k tomu, že u koček produkuje alfa koronaviry, liší se od koronaviru SARS-Cov-2, který u lidí produkuje COVID-19, beta alfavirus. FCoV se vyskytuje u koček chovaných v domácím i venkovním chovu. Míra infekce dramaticky stoupá v domácnostech s více vrhy ve srovnání s domácnostmi s jednou kočkou.

Přestože kočičí koronavirus (FCoV) způsobuje u koček pouze mírný průjem, jeho mutovaný kmen může vést k vážnému onemocnění, které může u koček vést k úmrtí. Asi u 10 % nakažených koček se rozvine infekce známá jako virus infekční peritonitidy koček (FIPV), která se může šířit po celém těle. Když se onemocnění zhorší, začne postihovat ledviny, břicho a mozek.

Infekční peritonitida koček je smrtelná virová infekce domácích a divokých koček způsobená specifickým kmenem viru zvaným kočičí koronavirus. Vzhledem k tomu, že u koček produkuje alfa koronaviry, liší se od koronaviru SARS-Cov-2, který u lidí produkuje COVID-19, beta alfavirus. FCoV se vyskytuje u koček chovaných v domácím i venkovním chovu. Míra infekce dramaticky stoupá v domácnostech s více vrhy ve srovnání s domácnostmi s jednou kočkou.

Přestože kočičí koronavirus (FCoV) způsobuje u koček pouze mírný průjem, jeho mutovaný kmen může vést k vážnému onemocnění, které může u koček vést k úmrtí. Asi u 10 % nakažených koček se rozvine infekce známá jako virus infekční peritonitidy koček (FIPV), která se může šířit po celém těle. Když se onemocnění zhorší, začne postihovat ledviny, břicho a mozek.

Clinical Signs of Feline Calicivirus

The clinical presentation of FCV varies depending on viral strain, immune response, and concurrent conditions.

Common Early Clinical Signs

  • Mild lethargy

  • Reduced appetite

  • Upper respiratory signs

  • Subtle oral discomfort

Progressive or Chronic Clinical Signs

  • Oral ulceration affecting the tongue, gingiva, or buccal mucosa

  • Severe gingivitis or stomatitis

  • Excessive salivation

  • Halitosis

  • Weight loss secondary to oral pain

Search queries such as feline calicivirus symptoms, calicivirus cat mouth, and FCV symptoms commonly reflect these findings.

Oral Disease and FCV: A Central Clinical Challenge

One of the most clinically significant aspects of feline calicivirus infection is its association with chronic inflammatory oral disease.

 

Observed manifestations may include:

  • Refractory gingivitis

  • Ulcerative stomatitis

  • Glossitis

  • Pain-associated dysphagia

 

Because cats frequently mask discomfort, diagnosis is often delayed until oral disease has progressed.

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Feline Calicivirus in Kittens and Adult Cats

FCV can affect cats at any life stage, though disease expression may differ.

  • Kittens may exhibit more pronounced systemic signs due to immature immune defenses

  • Adult cats are more likely to develop chronic or recurrent oral inflammation

  • Some cases present with transient lameness (“limping calici”)

  • Rarely, virulent systemic feline calicivirus may result in severe multisystemic illness

 

Early veterinary evaluation is particularly important in young or immunocompromised cats.

Why Management of Feline Calicivirus Is Complex

Many owners search for terms such as feline calicivirus treatment, calicivirus cure, or antibiotics for FCV. However, FCV presents unique clinical challenges.

 

Key considerations include:

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  • FCV is a viral infection, not a bacterial one

  • Antibiotics address secondary bacterial complications only

  • No single universally effective treatment exists

  • Chronic cases may require long-term management

 

As a result, care decisions depend heavily on veterinary assessment and individualized planning.

Veterinary Perspective on Managing FCV

From a clinical standpoint, management of feline calicivirus focuses on:

  • Diagnostic confirmation where appropriate

  • Monitoring disease progression and recurrence

  • Managing oral inflammation and discomfort

  • Supporting nutrition and overall quality of life

 

Search terms such as feline calicivirus diagnosis, FCV PCR, and feline calicivirus prognosis highlight the importance of professional veterinary involvement.

Antiviral Research and the Role of MolnuFIP

What Is MolnuFIP?

MolnuFIP is a veterinary-focused educational platform dedicated to increasing awareness of feline viral diseases and emerging antiviral research. The MolnuFIP website provides scientific context, veterinary perspectives, and research-based discussions related to antiviral approaches in feline medicine.

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MolnuFIP itself is not a medication and does not provide medical treatment. Its purpose is to support informed conversations between veterinarians and cat owners through education.

EIDD-1931 in Veterinary Antiviral Research

EIDD-1931 is an investigational antiviral compound studied in the context of RNA virus replication. Within veterinary research discussions, EIDD-1931 is referenced as part of broader scientific exploration into antiviral mechanisms that may be relevant to feline viral diseases, including feline calicivirus.

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Important context:

  • EIDD-1931 is discussed within research and veterinary frameworks only

  • Mention does not imply guaranteed outcomes or approval

  • Clinical decisions remain the responsibility of licensed veterinarians

Why Antiviral Research Matters in Chronic FCV

In some cats, persistent viral activity is believed to contribute to ongoing oral inflammation and delayed tissue healing. This understanding has led veterinary researchers to explore antiviral compounds—such as EIDD-1931—as part of efforts to better understand viral-driven disease processes.

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These discussions aim to:

  • Improve understanding of viral replication

  • Inform future veterinary research

  • Support long-term management strategies

Veterinary Oversight and Clinical Responsibility

Any consideration of antiviral compounds in cats must occur under strict veterinary supervision. Decisions depend on:

  • Confirmed diagnosis

  • Disease severity

  • Individual clinical response

  • Ongoing monitoring

Frequently Asked Questions About Feline Calicivirus

Is feline calicivirus contagious?
Yes. FCV is readily transmitted between cats, particularly in shared environments.

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Can vaccinated cats still develop FCV?
Vaccination may reduce disease severity but does not guarantee complete prevention.

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Is feline calicivirus fatal?
Most cats survive FCV infection, though chronic or severe cases require long-term management.

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Can FCV become a lifelong condition?
Yes. Some cats develop chronic or recurrent clinical signs.

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